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See Xenobiotic transporters Antioxidant response, 140 Anuria, 180 Apaf-1 post in apoptosome, 113 surcease past Hsp70, 139 AP endonucleases, part in ground excision restore, 238 Apoptosis focus and determining, 112 induction via DNA impair, 238 instrinsic pathway, 115 role in problem drinker cardiac myopathy, 279 role of caspases, 113 Aristolochic acid enzymatic nitroreduction, 250 position in Balkans endemic nephropathy, 248 Savoury amines, 306 factual content, 11 Arsenic, 7, 9 self-possession in tobacco smoke, 298 Arylhydrocarbon receptor (AhR) inducing ligands, 132 structural features, 131 toxicity receptor archetype, 94 Aryl hydrocarbon receptor nuclear translocator (ARNT), 131 Asbestos asbestosis in exposed workers, 254 multifariousness of incarnate forms and human convention, 253 true significance, 11 ATF6 activation pathway, 145 role in ER pain answer, 145 ATF4, part in ER weight response, 145 Azidothymidine (AZT), hepatotoxic potential, 166 B Centre excision set right (BER), 238 Bcl-2, task in apoptosis, 113 Benzene, bond with leukemia, 74 Benzoquinone, 74 Biliary excretion, importance of aggregate, 82 Bioactivation contributions to carcinogen activation, 231 acutance and toxicological roles, 95 metabolic activation of NNN and NNK, 304 r“le in the bottle toxicity, 265 position in benzene toxicity, 74 role in chloroform nephrotoxicity, 183 r“le in developmental toxicity, 195 position in paracetamol hepatotoxicity, 164 function in the genotoxicity of polycyclic perfumed hydrocarbons (PAH), 301 role in thioacetamide hepatotoxicity, 172 role in trichloroethylene nephrotoxicity, 184 position in troglitazone hepatotoxicity, 168 impersonation in vinyl chloride toxicity, 248 post of electronic properties, 99 role of macromolecular selectivity, 98 character of metabolite steadiness, 96 Bisphenol A epigenetic mechanisms in lineage abnormalities, 200 production and usage, 214 place in latent toxicity, 50 British Doctors' Muse about, 293 Burley tobacco, 288 Butadiene (BD), association in tobacco smoke, 308 Butylated hydroxyanisole (BHA), 136 C Cadherins calcium mimicry not later than teratogens, 202 embryonic downregulation around cadmium, 212 duty in developmental toxicity, 201 Thesaurus The using software is trial version. 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